What is Fanconi Anaemia

What is Fanconi Anaemia

Fanconi Anaemia (FA) is a rare, inherited blood disorder that leads to bone marrow failure. First described by the Swiss pediatrician, Guido Fanconi, FA prevents bone marrow from making enough new blood cells for your body to work normally. FA also causes bone marrow to produce abnormal blood cells that leads to serious health problems such as acute myeloid leukemia.

 

FA is a blood disorder, but it also affects many of the body’s organs, tissues and systems. Patients who have had a successful bone marrow transplant and, thus, are cured of the blood problems associated with FA still must have regular examinations to watch for signs of head and neck, esophageal, gastrointestinal, vulvar and anal cancers. Many FA patients do not reach adulthood.

 

FA occurs equally in males and females. It is found in all ethnic groups. The average life expectancy for a patient with FA is 24.7 years, although there are now patients living into their 30s, 40s and even 50s.